Product Name :
TRPV6 Rabbit Polyclonal Antibody
Predicted band size :
87 kDa
Observed band size :
42 kDa (unglycosylated monomeric form of TRPV6)
Synonyms:
ABP/ZF antibody ABPZF antibody Alu binding protein with zinc finger domain antibody Calcium channel CaT1 antibody Calcium transport protein 1 antibody CaT L antibody CaT Like antibody CaT-L antibody CaT-like antibody CaT1 antibody 展开
Function :
Calcium selective cation channel that mediates Ca2+ uptake in various tissues, including the intestine .3-Bromo-5-methylbenzonitrile web Important for normal Ca2+ ion homeostasis in the body, including bone and skin (By similarity). The channel is activated by low internal calcium level, probably including intracellular calcium store depletion, and the current exhibits an inward rectification . Inactivation includes both a rapid Ca2+-dependent and a slower Ca2+-calmodulin-dependent mechanism; the latter may be regulated by phosphorylation.N-Fmoc-3-iodo-L-alanine methyl ester Data Sheet In vitro, is slowly inhibited by Mg2+ in a voltage-independent manner. Heteromeric assembly with TRPV5 seems to modify channel properties. TRPV5-TRPV6 heteromultimeric concatemers exhibit voltage-dependent gating.
Antibody Type:
Rabbit Polyclonal Antibody
Immunogen :
Synthetic peptide corresponding to C terminal of Human TRPV6 .
Species reactivity:
Human, Mouse, Rat
Verify application:
WB, IHC-P, IF-Cell, FC
Coupling :
unconjugated
Clone number:
RRID:
AB_3071428
Form :
Liquid
Concentration :
1ug/ul
Storage instructions:
Store at +4℃ after thawing.PMID:33428479 Aliquot store at -20℃. Avoid repeated freeze / thaw cycles.
Storage buffer solution:
PBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Subtype:
IgG
Purification method :
Immunogen affinity purified.
ELTSA :
Molecular weight :
Predicted band size: 87 kDa
Positive control :
SW480 cell lysate, SK-Br-3 cell lysate, HepG2, HT-29, rat testis tissue, human kidney tissue, mouse colon tissue, human placenta tissue.