Product Name :
SPAK Recombinant Rabbit Monoclonal Antibody [JE53-64]
Predicted band size :
Observed band size :
Synonyms:
DCHT antibody DKFZp686K05124 antibody OTTHUMP00000165175 antibody PASK antibody Proline alanine rich STE20 related kinase antibody Serine threonine kinase 39 (STE20/SPS1 homolog yeast) antibody Serine threonine kinase 39 antibody Serine/threonine protein kinase 39 antibody Serine/threonine-protein kinase 39 antibody Small intestine SPAK like kinase antibody 展开
Function :
STE20/SPS1-related proline-alanine-rich protein kinase is an enzyme that in humans is encoded by the STK39 gene. This gene encodes a serine/threonine kinase that is thought to function in the cellular stress response pathway. The kinase is activated in response to hypotonic stress, leading to phosphorylation of several cation-chloride-coupled cotransporters. The catalytically active kinase specifically activates the p38 MAP kinase pathway, and its interaction with p38 decreases upon cellular stress, suggesting that this kinase may serve as an intermediate in the response to cellular stress. Some studies suggest that this gene might be linked to high blood pressure.
Antibody Type:
Recombinant Rabbit monoclonal Antibody
Immunogen :
Recombinant protein within Human SPAK aa 361-545 / 545.
Species reactivity:
Human
Verify application:
WB, IHC-P, FC
Coupling :
unconjugated
Clone number:
JE53-64
RRID:
AB_3071002
Form :
Liquid
Concentration :
1ug/ul
Storage instructions:
Store at +4℃ after thawing.5-Bromo-1H-pyrazolo[3,4-b]pyridine Order Aliquot store at -20℃.α-(Bromomethyl)-2-pyrazinemethanol custom synthesis Avoid repeated freeze / thaw cycles.PMID:33414521
Storage buffer solution:
1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Subtype:
IgG
Purification method :
Protein A affinity purified.
ELTSA :
Molecular weight :
Predicted band size: 59 kDa
Positive control :
Jurkat cell lysate, HepG2 cell lysate, human prostate carcinoma tissue, human pancreas tissue, Daudi.