Product Name :
2-Isocyanatothiophene (CAS 2048-57-9)
Synonym :
2-Thienyl isocyanate; thiophen-2-isocyanate
Application :
CAS:
2048-57-9
Purity:
≥85%
Molecular Weight:
125.15
Formula :
C5H3NOS
Physical state:
Liquid
solubility :
Shipping Condition :
Store at 4° C
Melting point:
-5.1075198-30-9 Chemscene 40° C (Predicted)
SMILES:
C1=CSC(=C1)N=C=O
References:
:Lead optimization of N-3-substituted 7-morpholinotriazolopyrimidines as dual phosphoinositide 3-kinase/mammalian target of rapamycin inhibitors: discovery of PKI-402.Nepsilon-Acetyl-L-lysine Formula | Dehnhardt, CM.PMID:33663341 , et al. 2010. J Med Chem. 53: 798-810. PMID: 19968288Bis(morpholino-1,3,5-triazine) derivatives: potent adenosine 5′-triphosphate competitive phosphatidylinositol-3-kinase/mammalian target of rapamycin inhibitors: discovery of compound 26 (PKI-587), a highly efficacious dual inhibitor. | Venkatesan, AM., et al. 2010. J Med Chem. 53: 2636-45. PMID: 20166697ZnCl2-Promoted Intramolecular Hetero-Diels-Alder Reaction of o-Alkynylphenylcarbodiimides for Synthesis of Dihydrodibenzo[b,g][1,8]naphthyridines. | Kutsumura, N., et al. 2016. Chem Pharm Bull (Tokyo). 64: 1364-9. PMID: 27321228Structural optimization and structure-activity relationship studies of N-phenyl-7,8-dihydro-6H-pyrimido[5,4-b][1,4]oxazin-4-amine derivatives as a new class of inhibitors of RET and its drug resistance mutants. | Yang, J., et al. 2018. Eur J Med Chem. 143: 1148-1164. PMID: 29133048