Product Name :
Tankyrase 2 Recombinant Rabbit Monoclonal Antibody [PSH0-53]
Predicted band size :
127 kDa
Observed band size :
127 kDa
Synonyms:
ADP-ribosyltransferase diphtheria toxin-like 6 antibody ARTD6 antibody PARP 5b antibody PARP 5c antibody PARP-5b antibody PARP-5c antibody PARP5B antibody PARP5C antibody pART6 antibody Poly [ADP ribose] polymerase 5B antibody 展开
Function :
Poly-ADP-ribosyltransferase involved in various processes such as Wnt signaling pathway, telomere length and vesicle trafficking. Acts as an activator of the Wnt signaling pathway by mediating poly-ADP-ribosylation of AXIN1 and AXIN2, 2 key components of the beta-catenin destruction complex: poly-ADP-ribosylated target proteins are recognized by RNF146, which mediates their ubiquitination and subsequent degradation.Buy1394003-65-6 Also mediates poly-ADP-ribosylation of BLZF1 and CASC3, followed by recruitment of RNF146 and subsequent ubiquitination. Mediates poly-ADP-ribosylation of TERF1, thereby contributing to the regulation of telomere length. Stimulates 26S proteasome activity.
Antibody Type:
Recombinant Rabbit monoclonal Antibody
Immunogen :
Recombinant protein within human Tankyrase 2 aa 451-700/1,166.
Species reactivity:
Human, Rat
Verify application:
WB, IF-Cell
Coupling :
unconjugated
Clone number:
PSH0-53
RRID:
AB_3072517
Form :
Liquid
Concentration :
1ug/ul
Storage instructions:
Store at +4℃ after thawing.BuyHex-5-yn-1-ol Aliquot store at -20℃.PMID:33506687 Avoid repeated freeze / thaw cycles.
Storage buffer solution:
PBS (pH7.4), 0.1% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Subtype:
IgG
Purification method :
Protein A affinity purified.
ELTSA :
Molecular weight :
Predicted band size: 127 kDa
Positive control :
PC-12 treated with 1μM XAV939 for 24 hours whole cell lysate, PC-12 treated with 1μM XAV939 for 48 hours whole cell lysate, A431.