Product Name :
SFRP1 Recombinant Rabbit Monoclonal Antibody [JA11-68]
Predicted band size :
35 kDa
Observed band size :
35 kDa
Synonyms:
Frizzled related protein 1 antibody FRP 1 antibody FRP antibody FRP-1 antibody FRP1 antibody FrzA antibody SARP 2 antibody SARP-2 antibody SARP2 antibody Secreted apoptosis related protein 2 antibody 展开
Function :
Soluble frizzled-related proteins (sFRPS) function as modulators of Wnt signaling through direct interaction with Wnts. They have a role in regulating cell growth and differentiation in specific cell types. SFRP1 decreases intracellular beta-catenin levels (By similarity). Has antiproliferative effects on vascular cells, in vitro and in vivo, and can induce, in vivo, an angiogenic response.1780637-40-2 Formula In vascular cell cycle, delays the G1 phase and entry into the S phase (By similarity).Boc-NH-C6-Br Price In kidney development, inhibits tubule formation and bud growth in metanephroi (By similarity).PMID:33590798 Inhibits WNT1/WNT4-mediated TCF-dependent transcription.
Antibody Type:
Recombinant Rabbit monoclonal Antibody
Immunogen :
Synthetic peptide within Human SFRP1 aa 31-80 / 314.
Species reactivity:
Human, Mouse
Verify application:
WB, IHC-P
Coupling :
unconjugated
Clone number:
JA11-68
RRID:
AB_3070480
Form :
Liquid
Concentration :
1ug/ul
Storage instructions:
Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles.
Storage buffer solution:
1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Subtype:
IgG
Purification method :
Protein A affinity purified.
ELTSA :
Molecular weight :
Predicted band size: 35 kDa
Positive control :
SH-SY5Y cell lysate, SK-MEL-28 cell lysate, NIH/3T3 cell lysate, Mouse kidney tissue lysate, human testis tissue.