Product Name :
Siah-1/2 Rabbit Polyclonal Antibody
Predicted band size :
Observed band size :
Synonyms:
E3 ubiquitin-protein ligase SIAH1 antibody FLJ08065 antibody hSIAH1 antibody HUMSIAH antibody Seven in absentia homolog 1 (Drosophila) antibody Seven in absentia homolog 1 antibody Siah 1 antibody Siah 1a antibody Siah E3 ubiquitin protein ligase 1 antibody Siah-1 antibody 展开
Function :
This gene encodes a protein that is a member of the seven in absentia homolog (SIAH) family. The protein is an E3 ligase and is involved in ubiquitination and proteasome-mediated degradation of specific proteins. The activity of this ubiquitin ligase has been implicated in the development of certain forms of Parkinson’s disease, the regulation of the cellular response to hypoxia and induction of apoptosis. Alternative splicing results in several additional transcript variants, some encoding different isoforms and others that have not been fully characterized.154775-43-6 In stock
Antibody Type:
Rabbit Polyclonal Antibody
Immunogen :
The antiserum was produced against synthesized peptide derived from human SIAH1.2,4,5-Trichloroquinoline web AA range:181-230
Species reactivity:
Human, Mouse, Rat
Verify application:
WB, IHC-P, IF
Coupling :
unconjugated
Clone number:
RRID:
Form :
Liquid
Concentration :
1ug/ul
Storage instructions:
Store at +4℃ after thawing.PMID:33459177 Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles.
Storage buffer solution:
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Subtype:
IgG
Purification method :
Immunogen affinity purified.
ELTSA :
Molecular weight :
34 kDa
Positive control :
Brain,Fetal brain,Intestinal epithelium,Pancreas,Retina,Testis,